Powerful HIV Antibodies May Require Assist from Second Antibody to Develop
NIAID-supported scientists have discovered that early in the course of HIV infection in one person, an ordinary HIV antibody influenced the virus to develop a mutation that helped a broadly neutralizing antibody develop its powerful HIV-fighting capability. Thus the process of antibody-HIV co-evolution can involve more than one antibody, a finding that may have implications for HIV vaccine design.
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