CDC - 2012 CRE Toolkit - HAI

CDC - 2012 CRE Toolkit - HAI

2012 CRE Toolkit - Guidance for Control of Carbapenem-resistant Enterobacteriaceae (CRE)

Carbapenem-resistant Enterobacteriaceae (CRE) are a serious threat to public health. Infections with CRE are difficult, and in some cases impossible, to treat and have been associated with mortality rates up to 50%(1). Due to the movement of patients throughout the healthcare system, if CRE are a problem in one facility, then typically they are a problem in other facilities in the region as well. To help protect patients and prevent transmission, CDC has released a CRE toolkit which expands on the 2009 CDC recommendations and continues to be updated as new information becomes available.

Guidance for Control of Carbapenem-resistant Enterobacteriaceae (CRE) - 2012 CRE Toolkit  [PDF - 2.98 MB]

See also – CRE Control and Prevention Toolkit

Table of Contents

• Introduction
• Background
• Definitions
• Part 1: Facility-level CRE Prevention
  • Surveillance
  • Facility-level Prevention Strategies
    • Core Measures for All Acute and Long-term Care Facilities.
    • Supplemental Measures for Healthcare Facilities with CRE Transmission
    • Recommendations for Facilities with No or Rare CRE
  • Summary of Prevention Strategies for Acute and Long-term Care Facilities
• Part 2: Regional CRE Prevention: Recommended Strategies for Health Department Implementation
  • Public Health Engagement
  • Regional Surveillance for CRE
  • Regional Prevention Strategies
    • Regions with No CRE Identified
    • Regions with Few CRE Identified
    • Regions Where CRE are Common
  • Appendix A: Previous and Current Clinical and Laboratory Standards Institute Interpretive Criteria for Carbapenems and Enterobacteriaceae
  • Appendix B: General Approach to Carbapenem-resistant Enterobacteriaceae(CRE) Control in Facilities that Rarely or Have Not Identified CRE
  • Appendix C: Example of a Survey for Infection Preventionists
  • Survey of Healthcare Facilities for Carbapenem-resistant Enterobacteriaceae (CRE)
    • Algorithm for Regions with No CRE Identified
    • Algorithm for Regions with Few CRE Identified
    • Algorithm for Regions Where CRE are Common
• Selected References

1. Refers to: Patel G, Huprikar S, Factor SH, Jenkins SG, Calfee DP. Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies. Infect Control Hosp Epidemiol 2008;29:1099-106.

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